Directly from IDW editor Andy Schmidt, courtesy of the IDW message boards:
The series does lead into CHAOS, and so do James Robert’s two issues of the ongoing series coming up (did I just say that? WHAT?).
James IS writing TRANSFORMERS #s 22 and 23.
For those who don’t know, James Roberts is half of the writing team (with Nick Roche) of the popular “Last Stand of the Wreckers” mini-series.